Characteristics of rifampicin-resistant tuberculosis detection in China, 2015–2019

Abstract Background The very high burden of rifampicin resistance tuberculosis (RR-TB) and the low detection RR-TB cases are a major challenge that China has been facing. This study analyzed characteristics in after change strategy since 2015, aiming to provide reference evidence for development more precise national drug prevention control policy. Methods We extracted data related screening from Tuberculosis Information Management System (TBIMS) 2015 2019, used descriptive research methods analyze rate presumptive RR-TB, number duration patients detected testing each year. Chi-square test was compare differences component ratio or between years, Kruskal Wallis median days Results A total 68,200 were during 2015–2019, which 48.1% new cases. increased year by year, 10 019 14.3% 18 623 28.7% respectively. Of bacteriologically confirmed TB cases, 81.9% tested RR considerable increase 29.5% 2015. In only 41.0% had fluoroquinolones (FQs) susceptibility performed, this proportion declining 2016. application rapid molecular tools 24.0% 67.1% obtain results significantly shortened. 76.0% diagnosed as county-level hospitals. Conclusions After modified strategy, significantly. now predominantly utilize tools. However, comprehensive measures should be implemented close gap It is imperative take FQs seriously effectively strengthen laboratory capacity Graphical